27 June, 2005 | Issue #4

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  Pharma, Biotechnology and Health

  • Half the world’s cotton may come from GM crops’
    June 21

    More than half the world’s cotton may be grown from genetically modified (GM) crops within two years as farmers in India and Brazil embrace the technology that promises to raise incomes and boost output, Rabobank Groep said.

    Increased usage of Monsanto Co’s Bollgard II and other gene-altered varieties may propel the proportion of cotton grown from biotech crops to more than 50% by 2006-07 from about 35% now, Utrecht, Netherlands-based Rabobank said in an e-mailed report on Monday.

    Scientists have developed cotton varieties that repel grubs and other pests, requiring less pesticide. A smaller chemical bill can lower farmers’ costs of production, boosting their incomes. Rising sales of the biotechnology in countries such as Brazil may bolster supplies amid a global glut of the fiber. “The expansion of GM production, particularly in regions which already operate under a fairly low-cost production system, will have long-term implications upon the marginal cost of production and, subsequently, prices,” Rabobank said in a May cotton industry report.

    Prices on the New York Board of Trade, the world’s biggest cotton futures market, slumped 40% last year after larger crops in the US and China swelled global supplies. Global output may exceed consumption by 2.5 million tonne in the year ending July 31, according to the US Department of Agriculture.

    India, the world’s third-largest cotton-grower, planted 550,000 hectare (1.36 million acre) of biotech crops last year, up 460% from a year earlier, Rabobank said.

    “Some estimates indicate that this area may officially double in 2005-06 to 1 million hectare and, coupled with a higher proportion of better performing seeds, there is talk of India surpassing US production in the near future to become the second-largest cotton producer globally behind China,” the bank said.

    St Louis-based Monsanto, the world’s biggest developer of genetically modified crops, said May 19 that it expects to sell enough biotech cotton in India to plant 2.5 million acre, double last year’s sales.

    Monsanto’s Bollgard seeds contain a protein from a soil microbe called Bacillus thuringiensis, or Bt, that protects the crop from bollworms. “Bollgard II technology offers cotton growers efficient, effective pest control with fewer pesticide applications than in conventional cotton crops,” Monsanto said.

     URL: http://www.financialexpress.com/fe_full_story.php?content_id=94458

  • India for fivefold biotech expansion
    Tuesday, June 21, 2005

    NEW DELHI: India plans to expand its biotechnology sector by fivefold over the next five years as part of an ambitious strategy outlined at BIO 2005, the world's largest biotech conference. Steps under consideration range from new financial incentives for scientific entrepreneurs to industry-friendly regulations for testing drugs on animals and people.

    Kapil Sibal, India's science minister, launched the government's strategy - intended to make India as successful in the life sciences as it has been in software and information technology. It will require substantial investment by foreign companies attracted by India's skilled scientific workforce and lower costs than in the west.

    Gautam Thapar, chairman of the Confederation of Indian Industry biotechnology committee, said the plan showed the government was listening to industry and working with it, rather than at cross purposes as so often in the past.

    The policy will introduce new tax incentives and grants for entrepreneurs starting or expanding biotech companies. The government's Department of Biotechnology aims to create and support at least 10 biotech parks with incubator units by 2010.

    These will be promoted by a new Biotechnology Parks Society of India modeled on the Software Technology Parks of India, which did a lot to smooth the path of foreign IT companies to the country.

    On the regulatory front, a crucial change in policy will allow companies for the first time to test drugs on "large animals" such as dogs. Indian authorities have restricted animal testing to rodents - a serious handicap, given that most regulatory authorities such as the U.S. Food and Drug Administration require new drugs to be tested for toxic effects on at least one non-rodent species.

    The revenues of India's biotechnology sector grew by 37 percent to $1.1 billion in 2004-05.

    http://www.siliconindia.com/shownewsdata.asp?newsno=28525&newscat=Technology

  • Pharma companies in India zoom in on Brazil market’
    OUR CORPORATE BUREAU
    Mumbai, June 22

    Brazil’s $8 billion pharmaceutical market is a hot destination for Indian companies owing to its high price structure and dearth of domestic companies. Strides Arcolab, which is planning a merger with Matrix Laboratories, has emerged the number one Indian player in this market with a market share of $48 million, with majors like Ranbaxy and Torrent in tow, said the company’s managing director Arun Kumar at the company’s AGM here on Wednesday.

    Speaking on the merger, Mr Kumar said that the new company, Matrix Strides Ltd, will be 100% export-oriented, but may examine an Indian acquisition to sell products in India in the future.

    The proposed merger will make the combined entity a fully integrated company with capabilities in both raw materials and finished goods. The new entity will have revenues of Rs 2,500 crore, making it the fifth largest pharma company in India after Ranbaxy, Sun, Cipla and Dr Reddy’s Laboratories.

    The merged entity will also be the fourth largest manufacturer of AIDS drugs in the country, alongwith Cipla, Ranbaxy and Aurobindo Pharma.

    Although AIDS drugs form only 5 % of Matrix and Strides combined revenue, it is expected to go up in the near future.

    URL: http://www.financialexpress.com/fe_full_story.php?content_id=94558

  • US approves Indian AIDS drugs
    CHIDANAND RAJGHATTA
    WEDNESDAY, JUNE 22, 2005 06:47:19 AM

    WASHINGTON: The US Food and Drug Administration (FDA) has approved generic versions of two major AIDS drugs made by Indian pharma companies, marking a shift in Washington's approach to fighting the worldwide scourge and a new dynamic with the Indian drug industry.

    The FDA announced Monday that it had "tentatively" approved nevirapine tablets which is manufactured by Ranbaxy Laboratories Limited, Gurgaon, and Aurobindo Pharma Limited, Hyderabad.

    Nevirapine is the first generic versions of Viramune Tablets made originally by Boehringer Ingelheim.

    Last week, the FDA had similarly approved Lamivudine, an antiretroviral Nucleoside Reverse Transcriptase Inhibitor (NRTIs) that stops the HIV from infecting uninfected cells in the body.

    Lamuvudine, which is also manufactured by the two Indian drug companies, is the first generic version of brand name drug Combivir made by GlaxoSmithKline.

    These are the first India-made anti-AIDS drugs to win FDA approval.

    Earlier this year, the FDA had approved an antiretroviral drug regimen manufactured by Aspen Pharmacare of South Africa, making it the first non-U.S.-based generic pharmaceutical company to win such a clearance.

    The FDA said its tentative approval means that although existing patents and/or exclusivity prevent the marketing of Aurobindo’s and Ranbaxy’s products in the United States, "these products meet all of FDA's quality, safety and efficacy standards required for marketing in the United States."

    For now though, the drugs are eligible to be considered for purchase and use outside the United States. In the immediate context, they will be available for purchase under the President Bush's $15 billion Emergency Plan for AIDS Relief (PEPFAR).

    The US approval comes amid efforts by New Delhi to push for a common protocol between the FDA and Indian government drug regulation agency which will allow Indian drug companies to have their products approved in India for sale in the US instead of having to wait for separate FDA clearance.

    In recent weeks, India's Health Minister Anbumani Ramadoss and Science and Technology Minister Kapil Sibal have both held talks with US officials to arrive at such an agreement.

    Both ministers said Washington has has been positive to their proposals but a lot more groundwork needs to be done for the deal to materialize.

    http://timesofindia.indiatimes.com/articleshow/1149041.cms

Disclaimer: This publication is not intended for commercial purpose. All the information
provided are compiled from the resources available from the websites and manuals published.
CII holds no responsibility for the accuracy of the information.

Edited by Moinudeen and Vineet
News-items compiled and contributed by Anuradha, Seema and Subodh.
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